Electronic Data Capture

For Trials, Delphi Studies, Routine Data Collection, and Discrete Choice Experiments.



About Us

Clinvivo is a University of Warwick spin-out company that was incorporated following a HEIF5 grant to fund the development of technology to allow trial participants and patients to complete health outcomes conveniently on their own mobile devices. Clinvivo offers data collection services for clinical trials, epidemiological studies, Delphi studies, routine data collection, and discrete choice experiments. We have developed technology to deliver these services with a strong emphasis on security and good GDPR management.




Products, Services, and Security

Our electronic Patient Reported Outcome (ePRO) software permits participants in trials, or any type of epidemiological research (cohort studies, cross-sectional designs, etc), to complete outcome measurement simply, and securely, using their own devices.

Participants download our free app from the Apple or Google app stores, or use their browser to enrol. Enrolled participants then receive reminders to complete follow-ups, as required. Questionnaires can be displayed in multiple languages if needed. ePRO is not only environmentally friendly, saving on waste and paper storage, but it also improves response rates, data accuracy, and reduces costs associated with double-data entry.

Consent (both for research, and for GDPR, if consent is your legal basis) may be taken in-app. You receive regular anonymised reports of completion rates and transfers of your encrypted data.

Clinvivo started life in a Clinical Trials Unit. Its staff have been involved in many large clinical trials and you will find us familiar with needs and requirements, and flexible so that our services can be optimised to work perfectly with your chosen design.

Clinvivo's Delphi study software sends links to your panel by e-mail, and informs panellists when the next round is ready. The software allows panel members to review round material, see their own ratings from previous rounds and aggregate panel ratings, and also selected anonymised comments you would like the panellists to review.

Clinvivo also offers a full data analysis service, using either the RAND/UCLA appropriateness method, or percentage-based methods, as you prefer. Delphi studies may seem methodologically unfamiliar at times, in that they are not the same as surveys and a panel is not the same as a sample. However, Clinvivo makes Delphi studies easy; we can provide consultation on methods and approach as and when needed, in addition to doing the quantitative analyses for you. We can also offer qualitative analysis services. Between rounds, and at the end of the study, we provide a full and detailed report containing all you will need to write your paper.

Clinvivo
Trial Screenshot

The context in which treatment management decisions have been made is often unknown. A stated preference-elicitation method, known as a discrete choice experiment (DCE), permits the measurement and quantification of value attributes that inform decision-making. For example, consider being at a sporting event during an interval when many from the crowd wish to purchase food. Factors that people consider when deciding what to buy may include the type of food available from stands, the price, and the length of the queue. By presenting vignettes of each offer and queue length, and asking a person to choose between scenarios, the values assigned to food-type, cost, and queue length, can be quantified as a factor of each attribute. We could also make the design 'adaptive', so that the presented choices change depending on the selections made (e.g. if someone never chooses a salad bar option, that can be removed to focus on what matters more to that person).

Clinvivo's DCE software permits straight-forward DCE designs, as well as adaptive designs, and real-time analysis of responses. The software can be used in a browser, or in our DCE app, which can be installed on tablets for use in health care settings.

Clinvivo's Datacatcher app allows the routine collection of data from patients in clinical practice. Consent and GDPR notices can be managed in-app, and questionnaires can be presented in multiple languages. Patients can be reminded to complete follow-up outcome measures using direct device notifications, in the case of our iOS and Android apps, or by e-mail notification, in the case a patient prefers to use a browser. Regular reports and transfers of encrypted data can be arranged as needed, and deletion of data from our servers can be arranged in-line with your requirements.

Strong security underpins everything we do at Clinvivo. It is a core difference that we believe puts clear blue water between our offer and other offers currently in the ePRO market. All of our services use encryption, with data being encrypted both in transit, and at rest. We do not store private encryption keys for clinical studies on data servers; in the unlikely event that our server security was ever breached, data would be unreadable without the private key. We can, if required, operate so that even we are unable to decrypt data (i.e. if you give us a public key, and only you hold the private encryption key - please note that in this case it would be important not to loose your key as the data would be unreadable and unrecoverable).

Our servers are contained within a ISO27001 certified data centre, which offers excellent physical access control and monitoring, including weight and face recognition through airlock entry, 24 hour manned video surveillance, and fire detection monitoring. We operate regular penetration tests, reviews of our security practices, and all staff receive training on data management and security.

We are experienced when it comes to working with GDPR requirements. We act as your data processor and we have standard data processor agreements to facilitate quick contracting. Our software also has facilities to consent participants in cases where your legal basis for processing personal data is consent.


Endorsements

"Clinvivo ran the electronic questionnaire and data capture for a complex discrete choice experiment that was run with the University of Aberdeen. They provided timely advice and quick work on all requests, and managed the technical difficulties of accessing a diverse target group. Rob and the team were very accessible at all points of the project. Thank you!"

Christopher Bassford
Consultant in Intensive Care Medicine
University Hospital Coventry

"Clinvivo were central to organisation and delivery of a national survey of prostate cancer care in our recent NIHR programme development grant. The Clinvivo team were excellent in their support and efforts to tailor their service to exactly what we wanted for our primary research. Their electronic design and analysis services were very useful in achieving our research goals on time. We would be very pleased to work with them again in the future."

Liam Bourke
Reader
Sheffield Hallam University

"Clinvivo conducted a large Delphi study for us. They were very professional and helpful and also really flexible. It helped that they understood the research process, as well as being able to do the programming to set the study up. When the study was up and running several people commented to us about the professional look of the on-line survey compared to others they had seen. I would highly recommend Clinvivo"

Sandra Eldridge
Professor of Biostatistics
Queen Mary University of London

"Clinvivo helped us with an e-Delphi which sought the views of an international panel over three rounds. It certainly made the task much easier than trying to do it manually (which I have done in the past!). They provided an efficient service, nothing was too much trouble and they willingly accommodated our specific requests."

Hilary Pinnock
Reader
University of Edinburgh


"Clinvivo conducted and analysed an international Delphi study for us. Their service was timely, flexible, and of excellent standard. Rob’s expertise in the Delphi method was also instrumental in helping us design the Delphi. Clinvivo's electronic platform is slick and robust. They conducted the Delphi with great efficiency and produced very detailed reports that are reproducible and secure. We managed to achieve 100% retention across a 3-round Delphi thanks to their reminder system. Highly recommended!"

Hopin Lee
Postdoctoral Research Fellow
University of Oxford
and James McAuley
Associate Professor
University of New South Wales

"Clinvivo developed tablet-based student surveys for our pilot trial in secondary schools. They were flexible, accommodating and always available to answer questions and provide support. It was clear throughout the project that Clinvivo’s team is extremely dedicated to their work, to rigorous research methods and to data security. They were a pleasure to work with."

Rebecca Meiksin
Research Fellow in Social Science
London School of Hygiene and Tropical Medicine

Contact Us

Address:
Chequers Barn ,
Chequers Hill,
Bough Beech,
Edenbridge,
TN8 7PD.
Email:
Telephone:
+44 (0) 16null22 37null068-1

Clinvivo Ltd is a company registered in England and Wales. Company No. 8340814.
Registered Office: Sportsman Farm, St. Michaels, Tenterden, Kent, TN30 6SY.

Copyright © Clinvivo Ltd. 2015-2020